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Wahls Paleo Diet and Progressive Multiple Sclerosis

Moderatorji: UrosS, Metka, Stasa, Grom

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UrosS

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Vnosov: 11011

Pridružen: Ne feb 28, 2010 17:17

Odgovor So feb 22, 2014 14:33

Wahls Paleo Diet and Progressive Multiple Sclerosis

Bodo naredili novo študijo.

Purpose
Based on favorable preliminary data from ongoing studies testing the safety and tolerability of a nutrition, exercise and neuromuscular electrical stimulation funded by Direct MS, the investigators are proposing a pilot study focused on the Wahls Paleo plus Diet and Wahls Diet intervention to usual care. The intent is to measure the effect size of a Wahls Paleo plus Diet and the effect size of the Wahls Diet in reducing fatigue and improving quality of life scores as measured by fatigue severity scale score and MS quality of life 54 physical and mental scores and various subscale scores. Inclusion criteria is the presence of fatigue and the diagnosis secondary and primary progressive MS, progressive relapsing MS or relapsing-remitting MS with an expanded disability status scale score (EDSS) score of 4.5 or greater but otherwise stable medically. The Wahls Paleo plus (ketogenic diet) and the Wahls diet (modified paleolithic diet) groups will be instructed in completing a daily food log and receive coaching from registered dieticians who are expert in motivational interviewing. The control group will receive usual care. Biomarkers of nutrient levels (e.g. vitamin) and inflammation, blood sugar and insulin levels will be monitored. Additional blood will be frozen for future analysis. Nutrient (e.g. vitamin and antioxidant) intake will be assessed using food frequency questionnaires and 24 hr diet recalls. Test of endothelial function will be done at baseline and 12 weeks. Outcome measures will be change in quality of life and fatigue, endothelial function and blood biomarkers between enrollment and end of study at 12 weeks. The hypotheses are that the diet intervention groups will experience reduced fatigue and improved quality of life and improved biomarkers 1) between zero and 12 weeks and that the wahls paleo plus (ketogenic diet) and the wahls diet (modified paleolithic diet) groups will experience more improvements in quality of life and reduced fatigue and in biomarkers than the usual care group experiences at 12 weeks. The usual care group will be given instruction in following both the wahls paleo plus and the wahls diet plans and how to utilize the daily food logs at the end of study visit. The usual care group will receive one nutrition coaching call to assist with implementation of the study diet.
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blossom

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Pridružen: Sr maj 08, 2013 11:01

Odgovor So feb 22, 2014 21:44

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

Me prav zanima kaj bodo ugotovili. Do sedaj so se pri zdravljenju MS še najbolj obnesla zdravila, pri ostalem pa zmernost. No, sladkorju in predelanemu se lahko vsi brez kakršnekoli škode odpovedo :)

Drugače pa znajo take spremembe prehrane povzročiti več škode kot koristi zaradi samega stresa za telo, ki pride zaradi spremembe prehrane.
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Grom

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Šefe

Vnosov: 63896

Pridružen: Če sep 23, 2004 18:35

Odgovor So feb 22, 2014 21:52

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

lahko preideš postopoma
ketogena je drugače v teh primerih že večrat uspela. Dr.Lutz in kwasniewski vem da sta v svojih klinikah zdravila tudi MS
Vabljeni na moje spletne strani: www.gaspergrom.com
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blossom

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Vnosov: 503

Pridružen: Sr maj 08, 2013 11:01

Odgovor So feb 22, 2014 22:08

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

Verjamem. Ampak po mojem mnenju je dejansko velik dejavnik to, ali človek določeno prehranjevanje sprejme, verjame vanj, ali pa ga že v osnovi zavrača. In pa od predhodne prehrane.
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Grom

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Šefe

Vnosov: 63896

Pridružen: Če sep 23, 2004 18:35

Odgovor So feb 22, 2014 22:15

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

če v prvih obdobjih ko se uvajaš ne verjameš da je možno definitvno težko prideš skozi proces prilagoditve
Vabljeni na moje spletne strani: www.gaspergrom.com
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blossom

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Senior Member

Vnosov: 503

Pridružen: Sr maj 08, 2013 11:01

Odgovor So feb 22, 2014 22:24

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

A imaš mogoče še kakšno drugo študijo o MS?
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Grom

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Šefe

Vnosov: 63896

Pridružen: Če sep 23, 2004 18:35

Odgovor So feb 22, 2014 22:30

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

Mislim da tukaj med drugim tudi omenja in maš pol reference.. nisem pa ziher


http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3321471/

The Ketogenic Diet as a Treatment Paradigm for Diverse Neurological Disorders
Carl E. Stafstrom1,2 and Jong M. Rho3,4,*
Author information ► Article notes ► Copyright and License information ►
This article has been cited by other articles in PMC.
Go to:
Abstract

Dietary and metabolic therapies have been attempted in a wide variety of neurological diseases, including epilepsy, headache, neurotrauma, Alzheimer disease, Parkinson disease, sleep disorders, brain cancer, autism, pain, and multiple sclerosis. The impetus for using various diets to treat – or at least ameliorate symptoms of – these disorders stems from both a lack of effectiveness of pharmacological therapies, and also the intrinsic appeal of implementing a more “natural” treatment. The enormous spectrum of pathophysiological mechanisms underlying the aforementioned diseases would suggest a degree of complexity that cannot be impacted universally by any single dietary treatment. Yet, it is conceivable that alterations in certain dietary constituents could affect the course and impact the outcome of these brain disorders. Further, it is possible that a final common neurometabolic pathway might be influenced by a variety of dietary interventions. The most notable example of a dietary treatment with proven efficacy against a neurological condition is the high-fat, low-carbohydrate ketogenic diet (KD) used in patients with medically intractable epilepsy. While the mechanisms through which the KD works remain unclear, there is now compelling evidence that its efficacy is likely related to the normalization of aberrant energy metabolism. The concept that many neurological conditions are linked pathophysiologically to energy dysregulation could well provide a common research and experimental therapeutics platform, from which the course of several neurological diseases could be favorably influenced by dietary means. Here we provide an overview of studies using the KD in a wide panoply of neurologic disorders in which neuroprotection is an essential component.
Vabljeni na moje spletne strani: www.gaspergrom.com
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Grom

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Šefe

Vnosov: 63896

Pridružen: Če sep 23, 2004 18:35

Odgovor So feb 22, 2014 22:35

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

Vabljeni na moje spletne strani: www.gaspergrom.com
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blossom

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Senior Member

Vnosov: 503

Pridružen: Sr maj 08, 2013 11:01

Odgovor So feb 22, 2014 23:03

Re: Wahls Paleo Diet and Progressive Multiple Sclerosis

Bom pregledala, hvala.

Vrni se na Paleo dieta

Kdo je prisoten

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